miRNA host gene expression in gliomas.

Host gene expression levels in gliomas were assessed by Affymetrix genechip hybridisation and normalized to the expression levels in control brain tissue. The expression levels of the mature miRNAs measured by real-time PCR (Table 1) are reported.*ratios below 0.33 are in italics.†ratios above 3 are in boldface.‡miRNA loci corresponding to miRNAs that showed coexpression with their host genes in normal tissue as reported [13] are underlined.§The 17 reported genes and transcribed regions host 19 different miRNA loci that code for 15 mature miRNAs.

胶质瘤宿主基因的表达水平通过Affymetrix基因芯片杂交技术进行评估，并将其标准化为对照脑组织中的表达水平。由实时PCR测量的成熟miRNA表达水平（见表1），其中比值低于0.33的以斜体表示，比值高于3的以粗体表示。†与正常组织中宿主基因共表达的miRNA位点（如文献[13]所述）以底线标注。‡所报告的17个基因和转录区域包含19个不同的miRNA位点，这些位点编码了15种成熟的miRNA。