官方服务:
资源简介:
Human ESC-based modeling of pediatric gliomas by K27M mutation in histone H3.3 variant
应用场景:
创建时间:
2025-01-24
相关数据集
Histone H3K36M mutation impairs mesenchymal differentiation and drives sarcoma development [RNA_H33_K36M_HMT]. Mus musculus
The goal of this study is to understand the alterations in transcriptome induced by histone H3K36M mutations Overall design: Transcritome profiling of 3 cell lines cultured in vitro and 6 murine tumor
NIAID Data Ecosystem100
Histone H3K36M mutation impairs mesenchymal differentiation and drives sarcoma development [RNA_H33_K36M_HMT]
The goal of this study is to understand the alterations in transcriptome induced by histone H3K36M mutations Overall design: Transcritome profiling of 3 cell lines cultured in vitro and 6 murine tumor
NIAID Data Ecosystem40
Human ESC-based modeling of pediatric gliomas by K27M mutation in histone H3.3 variant. Homo sapiens
Human diffuse intrinsic pontine gliomas (DIPG) are an aggressive form of pediatric brain tumors that arise in the pons in young children thus resulting in significant morbidity and very poor survival.
NIAID Data Ecosystem40
Histone H3G34R mutation causes replicative stress, defective homologous recombination and genomic instability in Fission Yeast
Recurrent somatic mutations of H3F3A in aggressive pediatric high-grade gliomas generate K27M or G34R mutant histone H3.3. H3.3-G34R mutants are common in tumors additionally mutant for p53 and ATRX,
NIAID Data Ecosystem60
A mutation in histone H2B Represents a new class of oncogenic driver
The goal of this study was to determine the mechanism by which a glutamate to lysine mutation of histone H2B at amino acid 76 (H2B-E76K), found particularly in bladder and head and neck cancer, may pr
NIAID Data Ecosystem40



