Ultrastructural damage is strongly reduced in persephone homozygotes versus wild-type siblings after neomycin exposure.

n = number of fish in each category.Damage scale:A = All hair cells of the neuromast appear normal.B = Slight mitochondrial swelling (modest within range of mock-treated controls).C = One or more hair cells exhibit some mitochondrial swelling. One or more hair cells also exhibit some nuclear condensation.D = Many hair cells show severe damage, including distended mitochondria, highly pycnotic nuclei, or condensation of the entire cell.E = Hair cells are absent, or all hair cells show severe damage, including severely distended mitochondria, highly pycnotic nuclei, or condensation of the entire cell.