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From Nitrobenzenes to Substituted Tetrahydroquinolines in a Single Step by a Domino Reduction/Imine Formation/Aza-Diels–Alder Reaction

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NIAID Data Ecosystem2026-03-08 收录
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The three-component reaction between a nitrobenzene, an aldehyde, and a dienophile in the presence of iron powder as a reductant and montmorillonite K10 as a catalyst in aqueous citric acid delivers the products of an aza-Diels–Alder (Povarov) reaction with high endo-selectivity and yields up to 99%.

创建时间:
2016-02-14
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