RNA-seq of cortical brain from Grin1-exon5 constitutive vs. Grin1-exon5 knockout mice

Here we report bulk RNA transcriptomes of cortical brains from transgenic mice from Grin1-exon5 constitutive vs. Grin1-exon5 knockout mice. Physiologically, Grin1-exon5 positive mice have reduced hippocampal LTP (vs. WT) and are learning and memory (vs. WT) impaired compared to Grin1-exon5 negative mice that have heightened LTP (compared to WT) and better learning and memory (compared to WT). Cortex from adult mice were sequenced using standard Illumina protocols.