For the two compounds whose pharmacokinetics is described by Eqs 3 and 4, the table lists the respective PK parameters: partition coefficients κ, permeabilities P, metabolization parameters Vmaxce
Background Declining in susceptibility of Plasmodium falciparum to mefloquine is reported in South-East Asia. A revisiting on mefloquine pharmacokinetics-pharmacodynamics (PK/PD) could assist in findi
Study objective The impact of biological sex in peripheral regional anaesthesia is largely unknown. We therefore designed a prospective study in volunteers to investigate the impact of biological sex
