Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket
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Crystal structure of catalytic domain of TACE with the first hydantoin inhibitor occupying the S1' pocket Descriptor: (5R)-5-[(5-methoxy-3-oxo-1,3-dihydro-2H-indazol-2-yl)methyl]-5-methylimidazolidine-2,4-dione, Disintegrin and metalloproteinase domain-containing protein 17, ZINC ION Authors: Orth, P. Deposit date: 2009-12-10 Release date: 2010-03-02 Last modified: 2024-11-20 Method: X-RAY DIFFRACTION (1.75 Å) Cite: Discovery and SAR of hydantoin TACE inhibitors. Bioorg.Med.Chem.Lett., 20, 2010
创建时间:
2009-12-10



