Pericentromeric heterochromatin is hierarchically organized and spatially contacts H3K9me2/3 islands located in genomic euchromatin

We aim to investigate the spatial contacts between heterochromatin domain and the euchromatic genome. We found that euchromatic transposable elements, which are usually associated with H3K9me2 enrichment, are in 3D contacts with the main heterochromatin domain genomic DNA sequencing of Drosophila melanogaster Oregon-R w1118