Transcriptome analysis of NKG2CBright compared to NKG2CNeg from multigravida decidua samples

In multigravidae, a specific dNK cell population characterized by NKG2CBright expression is expanded, suggesting that this reflects a population of memory dNK generated during the first pregnancy. Purpose: To gain further insight into the transcriptome profile of the expanded memory NKG2CBright dNK population found only in multigravida decidua samples Overall design: Flow cytometry based dNK cell sorting (based on CD56 and NKG2C) was done in order to purify CD56PosCD3NegCD16NegNKG2CBright and CD56PosCD3NegCD16NegNKG2CNeg subsets.