Predicted drug compounds for colorectal cancer adenoma.

The eight GO terms (biological function classifications) included are APO, CC, CP, ST, TR, DR, CP, RM and ISP (see abbreviations below). All drugs in the table have ES (enrichment score) <−0.75 (with only one exception). None of the drugs have harmful effects (ES >0) on any of the GO functions. Only compounds with up to 6 components are given. Abbreviations: ISP: immune system process – trifusal or morantel or gingolide or cetirizine or imipenem; APO: apoptosis – irinotecan or doxazosin or cycloserine or repaglinide; CC: cell cycle – doxorubicin or withaferin A; ST: signal transduction – 6-azathymine or tyloxapol; TR: transcription – sanguinarine; DR: DNA replication – piperlongumine; CP: Cell proliferation – bepridil; RM: RNA metabolic process – skimmianine; TDNA: transcription and DNA replication –chrysin or thioguanosine or luteolin or thiostrepton or sulconazole. The “degrees” in “Ratio of degrees” indicate the number of functional modules to which the corresponding component is beneficial.