Crystal Structure of PF10_0123, a GMP Synthetase from Plasmodium Falciparum

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疟原虫靶点结构

抗疟药物发现

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Crystal Structure of PF10_0123, a GMP Synthetase from Plasmodium Falciparum

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2023-09-13

Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor

抗疟药物发现

结构生物学

Plasmodium falciparum thymidylate kinase in complex with a urea-alpha- deoxythymidine inhibitor Descriptor: 1-[[(2R,3S,5S)-5-[5-methyl-2,4-bis(oxidanylidene)pyrimidin-1-yl]-3-oxidanyl-oxolan-2-yl]meth

Protein Data Bank Japan2023-12-20 更新60

Antimalarial compounds SMILES, InChI, 3D structure, CAS numbers

抗疟药物发现

化学信息学

Identifiers for the antimalarial compounds

Figshare2015-05-14 更新40

Catalyst and Additive-Free Diastereoselective 1,3-Dipolar Cycloaddition of Quinolinium Imides with Olefins, Maleimides, and Benzynes: Direct Access to Fused N,N′‑Heterocycles with Promising Activity against a Drug-Resistant Malaria Parasite

有机合成方法

抗疟药物发现

A convenient and eco-friendly synthesis of various fused N-heterocyclic compounds through catalyst and additive-free 1,3 dipolar cycloadditions of quinolinium imides with olefins, maleimides, and benz

Figshare2018-09-11 更新00

Additional file 5 of Development and experimental validation of a machine learning model for the prediction of new antimalarials

抗疟药物发现

机器学习预测

Supplementary Material 5

DataCite Commons2025-01-31 更新50

Pyrimidine Azepine Targets the Plasmodium bc 1 Complex and Displays Multistage Antimalarial Activity

抗疟药物发现

疟原虫机制研究

Malaria control and elimination efforts would benefit from the identification and validation of new malaria chemotherapeutics. Recently, a transgenic Plasmodium berghei line was used to perform a seri

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Crystal Structure of PF10_0123, a GMP Synthetase from Plasmodium Falciparum

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