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Single cell profiling of bone marrow adipocytes and bone marrow stromal cells from irradiated mice.

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NIAID Data Ecosystem2026-05-01 收录
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In order to comprehensively characterize bone marrow mesenchymal cells after myeloablation, single-nuclei RNA sequencing was performed on bone marrow adipocytes and bone marrow stromal cells isolated from sublethally-irradiated mice. Collected bone marrow adipocytes and sorted CD45/Ter119/CD31- cells from the bone marrow of Plin1-creER; tdTomato mice 5 weeks after sublethal irradiation were kept frozen until nuclei isolation. Cells were resuspended and extracted nuclei for single-nuclei RNA-seq (snRNA-seq).

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2023-10-30
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