Dati medico_sanitari_completi(1).sav

Anticholinergic Burden in adult and elderly people with Intellectual Disabilities.The 2012 updated version of the Anticholinergic Burden Score (ACB) was calculated for a multicentre sample of 276 adult and older people over 40 years with ID<br>and associations with factors assessed. Antipsychotics, antiepileptics, anxiolytics, and antidepressants were<br>the most frequent classes contributing to the total ACB score. Residential care setting was associated with higher exposure (ACB score 3+), both community housing (OR 4.63, 95%CI 1.08 - 19.95) and nursing home facility (OR 9.99, 2.32 - 43.04) as were a mental health (OR 25.56, 95% CI 8.08 - 80.89) and a neurological (OR 4.14, 1.32 - 12.94) condition. Age and gender were not significant nor were the other clinical conditions (somatic comorbidity, level and typology of ID). Higher anticholinergic load was significantly more frequent in laxative users (22.6% ACB3+ vs. 5.1% ACB 0)<br>(p=0.003).