Hypoxanthine phosphoribosyl transferase 1 metabolizes temozolomide to activate AMPK for chemoresistance of glioblastomas
收藏科学数据银行2023-08-14 更新2026-04-23 收录
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AUTHOR CONTRIBUTIONSX.Q., Z.L., and Y.Y. conceived and designed the study and interpreted the results. J.Y., X.F.W., X.G., F.D., Z.S., and Z.G. performed most of the experiments; G.H. and N.Z. performed the HPLC and mass spectrometry. D.C. provided support on MGMT analyses. J.Z., Y.C., and J.J. provided support on clinical analyses. S.A. and X.X.W. provided glioblastoma stem cells and technical supports. F.L., Q.W., and Q.Z. provided advices and regeants. X.Q. wrote the manuscript with comments from all authors.
提供机构：
Nanjing medical university
创建时间：
2023-06-25
