Figure S1 - Inverse Agonism of SQ 29,548 and Ramatroban on Thromboxane A2 Receptor

Flow cytometry analysis of cell surface receptor expression. Mean fluorescence intensity (MFI) and percentage positive cells (raw values) for WT and the mutant receptors before normalisation are shown. The bar graph shows the MFI (raw values) calculated from three independent experiments after deducting the negative control (cells mock transfected with vector alone). The table shows the average of the percentage positive cells expressing the receptor of interest after deducting the negative control (cells mock transfected with vector alone) from three independent experiments. Data are represented as Mean ± SD. The data is normalised to the WT-TP (3 µg of DNA) taken as 100%.
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