Analysys of the gut microbial diversity of CRC patients from Tunisia

The analysis of the human microbiome is an emerging research area of considerable interest regarding its role in human health and diseases. The microbiome refers to the genome of members of microbiota that is composed of billions of micro-organisms (bacteria, archaea, viruses and eukaryotic microbes). The microbiota lives inside the human body and affects many physiologic functions both in health and in disease. It is dynamic and subject to important changes during the host life in response to various factors including diet, environment, medical interventions, and disease states. Disruption of the microbial community, termed dysbiosis, constitutes a major risk factor for many diseases such as metabolic syndrome, immune disorders, cancer development, and is often directly linked to limited response to treatment.Our study's aim is Analyzing the microbiota diversity in our population in order to identify specific bacterial species that can be therapeutic candidates for personalized medicine in the future.