VCF files of the Nanopore gene sequencing of Colombian patients with apparent resistant hypertension (SCNN1A-SCNN1B-SCNN1G-CYP4A11)

We sequenced the DNA samples from 79 Colombian patients with apparent resistant hypertension. We were searching for clinically relevant genetic variants in the SCNN1A, SCNN1B, SCNN1G and CYP4A11 genes, which have been linked to the development of hypertension. We picked 7 random samples for the Nanopore sequencing of most of the coding region of SCNN1A, SCNN1B and SCNN1G genes. As all the 79 patients were from the same Colombian town of Puerto Tejada, we wanted to rule out the possibility of genetic variants common to this specific population. Moreover, in these 7 random samples, we sequenced most of the coding region of the CYP4A11 gene as well. Finally, in the 71 remaining samples, we only sequenced exon 2 through 12 of the CYP4A11 gene through Nanopore sequencing. The 7 VCF files ending in (1G-1B): contain the sequencing of SCNN1G (exon 7 to exon 13) and SCNN1B (exon 1 to exon 4) The 7 VCF files ending in (4A11-1A-1B-1G): contain the sequencing of SCNN1G (exon 2 to exon 6), SCNN1B (exon 5 to exon 12), SCNN1A (exon 5 to exon 13) and CYP4A11 (exon 2 to exon 12). The 71 remaining files, which end in (CYP4A11) contain the sequencing of CYP4A11 (exon 2 to 12) of the other 71 samples.