Structure of the C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant)
收藏Protein Data Bank Japan2023-12-27 更新2026-04-19 收录
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Structure of the C-terminal half of LRRK2 bound to GZD-824 (G2019S mutant) Descriptor: 4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}-3-[(1H-pyrazolo[3,4-b]pyridin-5-yl)ethynyl]benzamide, Designed Ankyrin Repeats Protein E11, Leucine-rich repeat serine/threonine-protein kinase 2 Authors: Villagran-Suarez, A, Sanz-Murillo, M, Alegrio-Louro, J, Leschziner, A. Deposit date: 2023-08-25 Release date: 2023-12-06 Last modified: 2023-12-27 Method: ELECTRON MICROSCOPY (2.99 Å) Cite: Inhibition of Parkinson's disease-related LRRK2 by type I and type II kinase inhibitors: Activity and structures. Sci Adv, 9, 2023
创建时间：
2023-08-25
