Universal_amplification__next_generation_sequencing_and_assembly_of_HIV_1_genomes
收藏NIAID Data Ecosystem2026-03-12 收录
下载链接：
https://www.ncbi.nlm.nih.gov/sra/ERP001257
下载链接
链接失效反馈官方服务：
资源简介：
Large-scale sequencing of RNA viruses such as HIV-1 is challenging due to the high genetic diversity and the need to generate substantial amounts of DNA. We report a universal method for amplification, next-generation sequencing and unbiased De Novo assembly of HIV-1 genomes that is independent of knowledge about sequence or subtype. We apply our approach to investigate HIV-1 diversity and to identify drug resistance mutations present at low frequencies.
创建时间：
2021-02-04
