Next Generation Sequencing Facilitates Quantitative Analysis of Control and rhCYGB treated in MIA PaCa-2 cell line

Purpose: The goal of this study is to investigate the inhibitor effect of Cytoglobin on pancreatic cancer Method: mRNA profiles of control and rhCYGB treated pancreatic cancer cells were generated by deep sequencing. Results: The RNA-seq data confirmed that extracellular matrix-encoding genes and cell cycle regulated genes were down-regulated by the His-CYGB treatment. mRNA profiles of MIA PaCa-2 cells with or without rhCYGB treatment