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TGF-β signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells

Alliance of Genome Resources2026-08-01 收录

内分泌干扰物毒性

子宫肌层干细胞DNA修复

数据链接：

https://www.ncbi.nlm.nih.gov/gds/?term=GSE225636 数据链接链接失效反馈

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资源简介：

The purpose of this study was to evaluate the impact of endocrine-disrupting chemicals (EDCs exposure on TGF-β1 pathway and nucleotide excision repair (NER) capacity, on Eker rat myometrial stem cells (MMSCs).

应用场景：

内分泌干扰物毒性

淡水鱼类毒理学

Prochloraz is a fungicide known to cause endocrine disruption through effects on the hypothalamic-pituitary-gonadal (HPG) axis. To determine the short-term impacts of prochloraz on gene expression and

NIAID Data Ecosystem30

Supplementary Materials for "Liquid Crystal Monomers and Their Mixtures Alter Nuclear Receptor Signaling and Promote Adipogenesis In Vitro"

内分泌干扰物毒性

细胞分化模型

This folder contains the supplementary materials for "Liquid Crystal Monomers and Their Mixtures Alter Nuclear Receptor Signaling and Promote Adipogenesis In Vitro". These include supplemental tables

Mendeley Data20

Evaluating the toxicity of two endocrine disrupting chemicals, Raloxifene and Resorcinol using a larval zebrafish transcriptomic approach. Evaluating the toxicity of two endocrine disrupting chemicals, Raloxifene and Resorcinol using a larval zebrafish transcriptomic approach

内分泌干扰物毒性

斑马鱼转录组毒理学

We use a larval zebrafish model to assess the transcriptomic alterations caused by sub-phenotypic concentrations of two endocrine disrupting drugs: Raloxifene and Resorcinol. Overall design: We use tw

NIAID Data Ecosystem20

Effect of maternal exposure to dioxin on the pituitary and hypothalamic expression of genes in PND70 male pups. Rattus norvegicus

内分泌干扰物毒性

神经内分泌基因调控

Our previous studies have revealed that treatment of pregnant rats with 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD, 1 μg/kg) at gestational day (GD) 15 reduces the pituitary synthesis of luteinizing ho

NIAID Data Ecosystem30

DataSheet_1_Intrauterine exposure to di(2-ethylhexyl) phthalate (DEHP) disrupts the function of the hypothalamus-pituitary-thyroid axis of the F1 rats during adult life.docx

内分泌干扰物毒性

甲状腺研究

IntroductionDEHP is an endocrine disruptor widely used in the production of malleable plastics. DEHP exposure was associated with altered hypothalamic-pituitary-thyroid (HPT) axis function. Although p

NIAID Data Ecosystem20

TGF-β signaling links early-life endocrine-disrupting chemicals exposure to suppression of nucleotide excision repair in rat myometrial stem cells

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