Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor
收藏Protein Data Bank Japan2023-11-22 更新2026-03-21 收录
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Crystal structure of TrmD from Mycobacterium tuberculosis in complex with active-site inhibitor Descriptor: tRNA (guanine-N(1)-)-methyltransferase, ~{N}-[[4-[(4-azanylpiperidin-1-yl)methyl]phenyl]methyl]-4-oxidanylidene-3~{H}-thieno[2,3-d]pyrimidine-5-carboxamide Authors: Zhong, W, Pasunooti, K.K, Balamkundu, S, Wong, Y.W, Nah, Q, Liu, C.F, Lescar, J, Dedon, P.C. Deposit date: 2019-03-20 Release date: 2019-09-04 Last modified: 2023-11-22 Method: X-RAY DIFFRACTION (2.2 Å) Cite: Thienopyrimidinone Derivatives That Inhibit Bacterial tRNA (Guanine37-N1)-Methyltransferase (TrmD) by Restructuring the Active Site with a Tyrosine-Flipping Mechanism. J.Med.Chem., 62, 2019
创建时间：
2019-03-20
