Additional file 6 of Dimethyl itaconate ameliorates cognitive impairment induced by a high-fat diet via the gut-brain axis in mice

Additional file 6: Table S1. 377 upregulated DEGs in the hippocampus between HF+Veh group mice and LC+Veh group mice. Table S2. 342 downregulated DEGs in the hippocampus between HF+Veh group mice and LC+Veh group mice. Table S3. 697 upregulated DEGs in the hippocampus between HF+DI group mice and HF+Veh group mice. Table S4. 185 downregulated DEGs in the hippocampus between HF+DI group mice and HF+Veh group mice. Table S5. Significantly enriched GO terms of upregulated DEGs between HF+DI group mice and HF+Veh group mice about biologic process. Only terms with a P < 0.05, minimum count of 3, and enrichment factor > 1.5 were considered significant. Table S6. Significantly enriched GO terms of upregulated DEGs between HF+DI group mice and HF+Veh group mice about cellular component. Only terms with a P < 0.05, minimum count of 3, and enrichment factor > 1.5 were considered significant. Table S7. KEGG pathways analysis of DEGs between HF+DI and HF+Veh groups. Table S8. Predicted KEGG functional pathway at level 1 inferred from 16S rRNA gene sequences using PICRUSt. Table S9. Predicted KEGG functional pathway at level 2 inferred from 16S rRNA gene sequences using PICRUSt. Table S10. Predicted KEGG functional pathway at level 3 inferred from 16S rRNA gene sequences using PICRUSt. Table S11. The qRT-PCR primer sequences used in this study.