Structure of cytochrome P450 2D6 (CYP2D6) BACE1 inhibitor complex
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Structure of cytochrome P450 2D6 (CYP2D6) BACE1 inhibitor complex Descriptor: (4S,6R)-4-[2,4-difluoro-5-({[1-(trifluoromethyl)cyclopropyl]amino}methyl)phenyl]-4,6-dimethyl-5,6-dihydro-4H-1,3-thiazin-2-amine, Cytochrome P450 2D6, PROTOPORPHYRIN IX CONTAINING FE, ... Authors: Hsu, M.H, Johnson, E.F. Deposit date: 2016-09-26 Release date: 2017-01-11 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (2.75 Å) Cite: Aminomethyl-Derived Beta Secretase (BACE1) Inhibitors: Engaging Gly230 without an Anilide Functionality. J. Med. Chem., 60, 2017
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2016-09-26
