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Glucose Metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo

ChEBI2013-02-15 更新2026-07-21 收录

干细胞发育

代谢调控机制

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43186 数据链接链接失效反馈

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资源简介：

Glucose Metabolism impacts the spatio-temporal onset and magnitude of HSC induction in vivo

应用场景：

创建时间：

2013-02-15

代谢调控机制

转录组学分析

This project reveals the role of Gcn4 in methionine dependent regulation of anabolic response. Using ChIP seq and RNA seq approaches, we identify the direct and indirect targets of Gcn4 under methioni

NIAID Data Ecosystem60

Crystal of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, soaked with allosteric activators AMP and Glucose 6-Phosphate

蛋白质晶体结构解析

代谢调控机制

Crystal of pyruvate kinase (PYK) from Mycobacterium tuberculosis in complex with Oxalate, soaked with allosteric activators AMP and Glucose 6-Phosphate Descriptor: 6-O-phosphono-alpha-D-glucopyranose,

Protein Data Bank Japan2023-11-08 更新40

Developmental cues license emergency megakaryopoiesis in hematopoietic stem cells [bulk RNA-seq & ATAC-seq]

干细胞发育

巨核细胞生成

The fetal to adult switch in mouse hematopoietic stem cell (HSC) behavior is characterized by entry into quiescence and alterations in lineage output. Here we identify the ability of HSCs to undergo e

NIAID Data Ecosystem40

Synergistic prostaglandin E synthesis by myeloid and endothelial cells promotes fetal hematopoietic stem cell expansion in vertebrates

干细胞发育

前列腺素信号通路

During development, hematopoietic stem cells (HSCs) are produced from the hemogenic endothelium, and will expand in a transient hematopoietic niche. Prostaglandin E2 (PGE2) is essential during vertebr

NIAID Data Ecosystem50

Melanocortin 3 receptor regulates hepatic autophagy and systemic adiposity

代谢调控机制

肥胖相关肝病

All figures and the underlying data for this manuscript.

Figshare2025-02-17 更新40