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Transcriptomic changes after orexin receptor antagonism in P301S/E4 mouse model of tauopathy

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NIAID Data Ecosystem2026-05-02 收录
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Our aim was to investigate whether increasing sleep via orexin receptor antagonism can modify tau-mediated neurodegeneration and neuroinflammation. Overall design: Cortex mRNA profiles of 41 weeks old P301S/E4 mice were generated by deep sequencing, in triplicate, using Illumina NovaSeq 6000.

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2025-02-26
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