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Deletion 9p drives B-cell leukemia by the concomitant loss of Pax5 and Cd72

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NIAID Data Ecosystem2026-05-10 收录
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The oncogenic role of 9p deletion in B-ALL has remained elusive since its discovery more than 40 years ago. We combined genomic analysis and functional models to show that the co-deletion of two contiguous genes, Pax5 and Cd72, confers gain in malignancy.

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2026-02-06
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