Contributions to buried surface area (BSA) in 2REB and 3CMW.

a Surface areas (Å2) of half-interfaces associated with each monomer A and B. b Region boundaries (detailed in Methods) were defined in order to minimize the RMSD difference between the two superposed rigid cores. Area differences with respect to reference [23] reflect differences in region definitions in addition to the neglect here of cofactor contributions. cfIR reports the fraction of rigid core residues from monomer A or B belonging to the interface in both 2REB and 3CMW forms. Contributions to buried surface area (BSA) in 2REB and 3CMW.