Multi-omics integration in mice with Parkinson's disease and the intervention effect of cyanidin-3-O-glucoside

In this study, the pharmacodynamic study of Cyanidin-3-O-glucoside in PD mice was applied. It intends to take the imbalance and balance of intestinal microecology as the starting point to investigate the gut-to-brain hypothesis using metabolomics combined 16S rRNA gene sequencing methods. Simultaneously, microbiome was performed to analyze the composition and filter the remarkable altered gut microbiota at the phylum/genera level.