Ovarian cancer epigenetically reprogram normal mesenchymal stem cells into carcinoma-associated mesenchymal stem cells (CA-MSCs). This reprogramming is characterized by enhancer-enriched DNA hypermeth
We investigated (a) the impact of canonical cancer driver genes (oncogenic Apc and Kras) on plasma membrane order and cholesterol homeostasis, and (b) the effect of cholesterol on modulating plasma me
Metastasis involves the dissemination of single or small clumps of cancer cells through blood or lymphatic vessels and their extravasation into distant organs. Despite the strong regulation of metasta