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bovine GRK2 in complex with human Gbetagamma subunits and CCG258208 (14as)

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Protein Data Bank Japan2023-10-04 更新2026-03-21 收录
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bovine GRK2 in complex with human Gbetagamma subunits and CCG258208 (14as) Descriptor: 5-[(3S,4R)-3-{[(2H-1,3-benzodioxol-5-yl)oxy]methyl}piperidin-4-yl]-2-fluoro-N-[(1H-pyrazol-5-yl)methyl]benzamide, Beta-adrenergic receptor kinase 1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Cruz-Rodriguez, O, Tesmer, J.J.G. Deposit date: 2017-01-23 Release date: 2017-04-12 Last modified: 2023-10-04 Method: X-RAY DIFFRACTION (3.03 Å) Cite: Structure-Based Design of Highly Selective and Potent G Protein-Coupled Receptor Kinase 2 Inhibitors Based on Paroxetine. J. Med. Chem., 60, 2017

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2017-01-23
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