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IS6110 insertion mutant in Rv0678 leading to Bedaquiline/clofazimine resistance

NIAID Data Ecosystem2026-05-10 收录

结核病耐药性

抗性突变

数据链接：

https://www.ncbi.nlm.nih.gov/sra/SRP676230 数据链接链接失效反馈

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资源简介：

Selection of Bedaquiline resistant mutant with IS6110 insertion in Rv0678 gene

应用场景：

创建时间：

2026-02-12

结核病耐药性

基因组测序诊断

India has a high burden of drug-resistant tuberculosis (DR TB) and many cases go undetected by current drug susceptibility tests (DSTs). This study was conducted to identify rifampicin (RIF) and isoni

NIAID Data Ecosystem30

Drug sensitivity testing and GeneXpert assay data.

结核病耐药性

GeneXpert分子诊断

TBwoHIV: Drug sensitivity testing and GeneXpert assay data in the TB without HIV infection group; TB-HIV: Drug sensitivity testing and GeneXpert assay data in the TB-HIV coinfection group. (XLSX)

NIAID Data Ecosystem20

GenoType MTBDRplus Assay for Rapid Detection of Multidrug Resistance in Mycobacterium tuberculosis: A Meta-Analysis

结核病耐药性

分子诊断

BackgroundThere is an urgent demand for rapid and accurate drug-susceptibility testing for the detection of multidrug-resistant tuberculosis. The GenoType MTBDRplus assay is a promising molecular kit

Figshare2016-03-08 更新10

CRyPTIC. CTB/NICD. Gates_clinical_isolates

结核病耐药性

临床分离株

CRyPTIC. CTB/NICD. Gates_clinical_isolates

NIAID Data Ecosystem20

Biochemical and antibiotic susceptibility profiles observed for M. tuberculosis complex reference strains and clinical isolates in this study

结核病耐药性

药物敏感性

T: type strain, +: positive results, -: negative results, R: drug resistant, S: drug susceptible, TCH: thiophene-2-carboxylic acid hydrazide (5 µg/ml), PZA: pyrazinamide (50 µg/ml).

NIAID Data Ecosystem20

IS6110 insertion mutant in Rv0678 leading to Bedaquiline/clofazimine resistance

资源简介：

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