Structural Basis for the Selective Pb(II) Recognition of Metalloregulatory Protein PbrR691
收藏NIAID Data Ecosystem2026-03-09 收录
下载链接：
https://figshare.com/articles/dataset/Structural_Basis_for_the_Selective_Pb_II_Recognition_of_Metalloregulatory_Protein_PbrR691/4272077
下载链接
链接失效反馈官方服务：
资源简介：
The transcription
regulator PbrR691, one of the MerR family proteins, shows extremely
high sensitivity and selectivity toward Pb(II) in Ralstonia
metallidurans CH34. Here, we present the crystal structure
of PbrR691 in complex with Pb(II) at 2.0 Å resolution. The Pb(II)
coordinates with three conserved cysteines and adopts a unique trigonal-pyramidal
(hemidirected) geometry. To our knowledge, the PbrR691-Pb(II) structure
provides the first three-dimensional visualization of a functional
hemidirected lead(II) thiolate coordinate geometry in a protein.
创建时间：
2016-11-30
