five

Functionalized Oxepines via Fragmentation of Highly Strained Epoxides

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https://figshare.com/articles/dataset/Functionalized_Oxepines_via_Fragmentation_of_Highly_Strained_Epoxides/3048937
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Epoxidation of highly strained cyclobutenes followed by thermal rearrangement provides a new entry into oxepine-containing bicyclo[5.3.0] ring systems. In contrast to the rearrangement of the corresponding cyclopropanated systems, the strained epoxides in this study are believed to fragment through two competing pathways leading to a mixture of diastereomeric 5-7 ring systems.
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2016-02-29
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