A Facile Synthesis of the Basic Steroidal Skeleton Using a Pauson−Khand Reaction as a Key Step
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A high-yield synthesis of steroid-type molecules under mild reaction conditions is achieved in two steps involving nucleophilic addition of alkynyl cerium reagent to an easily enolizable carbonyl compound (β-tetralone) followed by an intramolecular Pauson−Khand reaction.
创建时间:
2006-10-13



