DNA methylation analysis of epigenome-edited mice
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下载链接：
https://www.ncbi.nlm.nih.gov/sra/DRP005982
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资源简介：
We validate three methods for the generation of epigenome-edited mice using the dCas9-SunTag and single-chain variable fragment-TET1 catalytic domain. We generate model mice for Silver-Russell syndrome, an imprinting disorder, by target-specific DNA demethylation in the H19 differentially methylated region.
创建时间：
2020-05-21
