Supplementary Material for: International Consensus Statement on Screening, Diagnosis and Treatment of Substance Use Disorder Patients with Comorbid Attention Deficit/Hyperactivity Disorder

Adult attention deficit/hyperactivity disorder (ADHD) often co-occurs with substance use disorders (SUD) and is associated with early onset and more severe development of SUD and with reduced treatment effectiveness. Screening tools allow for a good recognition of possible ADHD in adults with SUD and should be used routinely, followed by an ADHD diagnostic process initiated as soon as possible. Simultaneous and integrated treatment of ADHD and SUD, using a combination of pharmaco- and psychotherapy, is recommended. Long-acting methylphenidate, extended-release amphetamines, and atomoxetine with up-titration to higher dosages may be considered in patients unresponsive to standard doses. This paper includes evidence- and consensus-based recommendations developed to provide guidance in the screening, diagnosis and treatment of patients with ADHD-SUD comorbidity.

成年注意力缺陷/多动障碍（ADHD）常与物质使用障碍（SUD）并存，并与SUD的早期发病和更严重的进展相关，且治疗效率降低。筛查工具有助于对患有SUD的成年人中可能存在的ADHD进行良好识别，应常规使用，并尽快启动ADHD的诊断过程。建议采用药物和心理治疗的结合，对ADHD和SUD进行同步和综合治疗。对于对标准剂量无反应的患者，可以考虑使用长效甲基苯丙胺、缓释安非他命和选择性5-羟色胺再摄取抑制剂，并逐步增加剂量。本文包括基于证据和共识的推荐，旨在为ADHD-SUD共病患者的筛查、诊断和治疗提供指导。