BRAF in Complex with RAF709
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BRAF in Complex with RAF709 Descriptor: N-{2-methyl-5'-(morpholin-4-yl)-6'-[(oxan-4-yl)oxy][3,3'-bipyridin]-5-yl}-3-(trifluoromethyl)benzamide, Serine/threonine-protein kinase B-raf Authors: Mamo, M, Appleton, B.A. Deposit date: 2017-03-27 Release date: 2017-06-28 Last modified: 2024-03-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Design and Discovery of N-(2-Methyl-5'-morpholino-6'-((tetrahydro-2H-pyran-4-yl)oxy)-[3,3'-bipyridin]-5-yl)-3-(trifluoromethyl)benzamide (RAF709): A Potent, Selective, and Efficacious RAF Inhibitor Targeting RAS Mutant Cancers. J. Med. Chem., 60, 2017
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2017-03-27
