FAIRsharing record for: MatrisomeDB

This FAIRsharing record describes: MatrisomeDB is a searchable collection of curated proteomic datasets focused on the analysis of the extracellular matrix (ECM) of healthy and diseased tissues.
In brief ECM proteomics datasets are retrieved from public repositories and are reprocessed using unified search parameters and criteria to allow inter-study comparison.
Users can search MatrisomeDB by inputting gene symbol(s), protein name(s), species, and/or tissue type(s).
The output from the data reprocessing workflow is displayed in the form of a downloadable table and different hierarchically-clustered distribution heatmaps computing confidence scores and protein abundance. Additional features include peptide mapping on primary amino-acid sequences, domain-based representation of proteins, and 3D protein structures. Users are also provided with references to external databases including GeneCard, UniProt, the CPTAC assay portal, and the Peptide Atlas, and with link to original publications and raw mass spectrometry data files.