Crystal structure of the B3 metallo-beta-lactamase L1 with hydrolysed ertapenem

Crystal structure of the B3 metallo-beta-lactamase L1 with hydrolysed ertapenem Descriptor: (2~{S},3~{R},4~{S})-2-[(2~{S},3~{R})-1,3-bis(oxidanyl)-1-oxidanylidene-butan-2-yl]-4-[(3~{S},5~{S})-5-[(3-carboxyphenyl)carbamoyl]pyrrolidin-3-yl]sulfanyl-3-methyl-3,4-dihydro-2~{H}-pyrrole-5-carboxylic acid, Metallo-beta-lactamase L1, SULFATE ION, ... Authors: Hinchliffe, P, Spencer, J. Deposit date: 2021-03-26 Release date: 2021-10-13 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (1.45 Å) Cite: Crystallography and QM/MM Simulations Identify Preferential Binding of Hydrolyzed Carbapenem and Penem Antibiotics to the L1 Metallo-beta-Lactamase in the Imine Form. J.Chem.Inf.Model., 61, 2021