Gut Microbiota and Transcriptome Dynamics in Every-Other-Day Fasting are Associated with Neuroprotection in Rats with Spinal Cord Injury. Rattus norvegicus

Every-other-day fasting (EODF) is a classical intermittent fasting (IF) mode with neuroprotective effects that promotes motor function recovery after spinal cord injury (SCI) in rats. However, its dynamic effects on the gut microbiota and spinal cord transcriptome remain unknown. Hence, the current study investigated the effects of ad libitum (AL) and EODF dietary modes on the structural characteristics of rat gut microbiota in rats and the spinal cord transcriptome at various time pointsafter SCI induction.