BDNF as Predictor Biomarker for pediatric Cerebral Palsy patients

A total of 75 Egyptian children were enrolled in this study, 45 were cerebral palsy and 30 were controls. CBC, ESR, C-reactive protein (CRP), BDNF, and TNF-α were assessed. Results: The erythrocytic sedimentation rate (ESR), CRP and TNF-α showed a statistically significant increase in cases compared to controls. While the Neutrophils/lymphocytes ratio and the BDNF levels were significantly lower in CP compared to controls. When comparing the different groups of CP with each other; there was no significant difference. Regarding the correlation of BDNF and different studied parameters, our study showed positive correlation between BDNF and TNF level only with spastic CP group.