Integrated transcriptomic and in silico analysis prioritizes AR and CTSK as candidate dehydrocostus lactone-related targets in triple-negative breast cancer

This repository contains the reproducibility package associated with the manuscript entitled "Integrated transcriptomic and in silico analysis prioritizes AR and CTSK as candidate genes emerging from dehydrocostus lactone target prediction and triple-negative breast cancer transcriptomics". It includes processed result tables, manuscript-related figure files, selected raw/reference input files, R session information, analysis command history, and docking parameter records corresponding to the reported discovery analysis, target-overlap analysis, independent validation in GSE65194, TCGA-BRCA survival analysis, AR-high versus AR-low TNBC GSEA, and molecular docking analyses. Public raw data were obtained from GEO (GSE270721 and GSE65194), UCSC Xena, and the Genomic Data Commons.