Juvenile Idiopathic Epilepsy in Arabian horses is not a single-gene disorder

Juvenile Idiopathic Epilepsy is characterized by tonic-clonic seizures in young Egyptian Arabian foals. The common signs include, disorientation and seizures which can sometimes lead to death and temporary blindness. Some foals grow out of the condition while others do not. Based on veterinary diagnosis, we included 180 horses (60 cases, 120 controls) for genotyping on the Affymetrix 670k genotyping array. A GWAs was performed on a genetically matched 1:2 case/control set, totaling 180 individuals using a GRM. We also performed two separate GWAS for coat color to test the efficacy of the JIE GWAS. This dataset includes genotypes for horses that passed the minor allele frequency of 0.05 and genotyping rate above 95%.