Supplementary Materials Data Availability.

Electrical acupoint stimulation (EAS) is proposed as a potentially beneficial treatment for patients suffering from knee osteoarthritis (KOA). This systematic review and meta-analysis aims to assess the assess the effectiveness and safety of EAS for KOA. To identify eligible RCTs, a systematic search for eligible RCTs is conducted through 6 November 2024 in 12 electronic literature databases, utilizing relevant keywords. The analysis applies a random-effects model to compute RRs and 95% CIs for the dichotomous outcome, alongside the SMD and 95% CIs for continuous outcomes. This meta-analysis includes 63 RCTs with a total of 6475 participants. The pooled analysis reveals that EAS increases the overall response rate by 19.5% (RR: 1.195, 95% CI: 1.130 to 1.264, P