Whole-genome sequencing of polyamine over-producing yeast strains

Dataset aims to uncover beneficial mutations on yeast strains (CEN.PK 113-11D based) engineered for polyamine over-production. We observed substantial heterogeneity between colony sizes and polyamine titers obtained between parent and final strains. Further physiological characterization of re-streaked colonies confirmed this phenotype, meaning that the sudden heterogeneity is heritable. Sequencing data presented here is used for identification differences between these mutated and parental strains.