补充图 S1-S6 和补充表。miRNA-150-5p 的 S1-S9 作为 sPTL 的生物标志物。

miR-150-5p was identified as a potential non-invasive biomarker associated with sPTL and regulates chorionic cell migration, invasion and adhesion by targeting ADAM19, a member of the ADAM family, contributing to premature rupture of fetal membranes. These findings provide new insights into the molecular mechanisms of sPTL and suggest that targeting the miR-150-5p/ADAM19 axis may offer novel therapeutic strategies.