首页/数据集/Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A.. Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A.

Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A.. Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A.

NIAID Data Ecosystem2026-05-01 收录

DNA修复

转录-复制冲突

数据链接：

https://www.ncbi.nlm.nih.gov/bioproject/PRJNA1058403 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Overall design: Refer to individual Series

应用场景：

创建时间：

2023-12-28

转录-复制冲突

R-loop解析机制

Fine-tuning DNA replication and transcription is crucial to prevent collisions between their machineries. This is particularly important near promoters, where RNA polymerase II (RNAPII) initiates tran

NIAID Data Ecosystem70

Structure of human DNA polymerase beta complexed with dzA as the template base in a 1-nucleotide gapped DNA

DNA修复

聚合酶结构

Structure of human DNA polymerase beta complexed with dzA as the template base in a 1-nucleotide gapped DNA Descriptor: DNA (5'-D(*CP*CP*GP*AP*CP*(4DU)P*TP*CP*GP*CP*AP*TP*CP*AP*GP*C)-3'), DNA (5'-D(*G

Protein Data Bank Japan2023-10-18 更新60

Homologous and Nonhomologous Recombination Resulting in Deletion: Effects of p53 Status, Microhomology, and Repetitive DNA Length and Orientation

基因组稳定性

DNA修复

Repetitive DNA elements frequently are precursors to chromosomal deletions in prokaryotes and lower eukaryotes. However, little is known about the relationship between repeated sequences and deletion

PubMed Central30

Crystal structure of human RECQL5 helicase APO form.

蛋白质晶体

DNA修复

Crystal structure of human RECQL5 helicase APO form. Descriptor: ATP-dependent DNA helicase Q5, ZINC ION Authors: Newman, J.A, Aitkenhead, H, Savitsky, P, Krojer, T, von Delft, F, Arrowsmith, C.H, Edw

Protein Data Bank Japan2024-05-08 更新70

PRMT5 regulates the homologous recombination DNA repair pathway by controlling the alternative splicing of key epigenetic factors. PRMT5 regulates the homologous recombination DNA repair pathway by controlling the alternative splicing of key epigenetic factors

DNA修复

表观遗传学

We found that PRMT5 deletion or inhibition impairs homologous recombination (HR) DNA repair, leading to DNA damage accumulation, p53 activation, cell cycle arrest and cell death through missplicing of

NIAID Data Ecosystem40

Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A.. Dynamic Control of RNA-DNA Hybrid Formation Orchestrates DNA2 Activation at Stalled Forks by RNAPII and DDX39A.

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