CDK2/CyclinE bound to compound 20 with P-loop in the EE and CC conformations

CDK2/CyclinE bound to compound 20 with P-loop in the EE and CC conformations Descriptor: (1R,3R)-3-{3-[3-(pyridin-3-yl)propanamido]-1H-pyrazol-5-yl}cyclopentyl (1-methylcyclopropyl)carbamate, Cyclin-dependent kinase 2, G1/S-specific cyclin-E1 Authors: Baird, J, Holliday, M.J. Deposit date: 2025-04-22 Release date: 2025-04-30 Last modified: 2026-05-06 Method: X-RAY DIFFRACTION (2.1 Å) Cite: Nanoscale Direct-to-Biology Optimization of Cdk2 Inhibitors. J.Med.Chem., 69, 2026