BindingDB Entry 50031834: New pyrazolo[1,5a]pyrimidines as orally active inhibitors of Lck.

Small molecule binding data for protein AKT/p21CIP1, ALK tyrosine kinase receptor, CDK2/Cyclin A/Cyclin A1, Epidermal growth factor receptor, Epidermal growth factor receptor and ErbB2 (HER1 and HER2), Fibroblast growth factor receptor 3, Hepatocyte growth factor receptor, Insulin receptor, Insulin-like growth factor I receptor, JAK3/JAK1, Kinesin-1 heavy chain/ Tyrosine-protein kinase receptor RET, Lysyl-tRNA synthetase, Platelet-derived growth factor receptor, Pyruvate dehydrogenase kinase isoenzyme 1 (PDK1), SRC, Tyrosine-protein kinase ABL1, Tyrosine-protein kinase JAK1, Tyrosine-protein kinase JAK2, Tyrosine-protein kinase Kit (Kit), Tyrosine-protein kinase ZAP-70, VEGF-receptor 2 and tyrosine-protein kinase SRC, Vascular endothelial growth factor receptor 2, and Vascular endothelial growth factor receptor 2 and tyrosine-protein kinase TIE-2 (KDR and TIE2), Uniprot O60674, P00519, P00533, P04626, P06213, P06239, P07949, P08069, P08581, P08631, P10721, P12931, P16234, P20248, P22607, P23458, P24941, P31749, P35968, P43403, P52333, P78396, Q02763, Q15046, Q15118, and Q9UM73